Preheat the oven to 350°F (175°C) and grease a 9x13-inch baking pan.
In a large bowl, beat butter, cream cheese, brown sugar, and granulated sugar until smooth; add eggs and vanilla extract, mixing well.
Stir in flour, baking soda, baking powder, cornstarch, and salt, then add buttermilk and mix until combined.
Spread half the batter into the pan, layer with lemon pie filling, and top with the remaining batter.
For the cream cheese filling, beat cream cheese, sugar, egg, lemon zest, and lemon juice until smooth, then dollop over the batter.
Prepare crumble topping by mixing flour, brown sugar, granulated sugar, cinnamon, and melted butter; sprinkle over the top, bake for 45-50 minutes, then cool and drizzle with glaze made from powdered sugar and milk.